Research Updates

SICKLE CELL DISEASE RESEARCH AMONG TOP 10 CLINICAL RESEARCH ACHIEVEMENTS OF 2012

Pioneering research led by Johns Hopkins scientists on the use of partially matched bone marrow transplants to wipe out sickle cell disease has been selected as one of the Top 10 Clinical Research Achievements of 2012 by the Clinical Research Forum. The success of a preliminary clinical trial of the so-called haploidentical transplants has the potential to bring curative transplants to a majority of sickle cell patients who need them, eliminating painful and debilitating symptoms and the need for a lifetime of pain medications and blood transfusions. more

The NHLBI and Sickle Cell Disease

The NHLBI is supporting research on more and better treatments to ease the burden of sickle cell disease on those affected. Trials using new bone marrow and stem-cell transplant procedures have cured a small number of some adults with sickle cell disease. More research is needed to understand possible health implications of sickle cell trait. more

Could an Old Antidepressant Treat Sickle Cell Disease?

An antidepressant drug used since the 1960s may also hold promise for treating sickle cell disease, according to a surprising new finding made in mice and human red blood cells by a team from the University of Michigan Medical School. more